The Research Behind Their Benefits
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Scientific research has proven the benefits of adaptogens on the human body. Adaptogens are biological substances found in certain rare plants and herbs that help the body "adapt" to changes and stress. Some of the benefits include overall stress protection, better ability to cope with stress, better sleep, quicker injury recovery, increased energy, and overall mental clarity and perception. The risks are zero, and existing scientific experiments verify this safety record.
Adaptogens were secretly researched and developed over the past 45 years by hundreds of scientists in the former Soviet Union. One to three billion dollars were spent in the Soviet quest for naturally occurring substances that would improve performance without side effects. It was used to improve performance in their Olympic athletes, cosmonauts, key military figures, chess champions and other performing elite. Although adaptogens are still relatively new to Americans, there are thousands of scientific studies documenting the benefits of including adaptogens in the diet.
The world renowned Russian research pharmacologist and physiologist, Dr. Israel Brekhman MD., is the discoverer of Adaptogens, and holds 40 patents on this discovery. He taught the Soviet scientific community what they had to offer to humans. Dr. Brekhman's research was secret but significant, and applied with great success in the diets of Soviet cosmonauts and Olympic athletes to show off their superiority to the world.
A few years ago, Dr. Brekhman formed an exclusive collaboration with PrimeQuest International, made possible by the breakup of the USSR. They created programs based on his experience, knowledge and vision. They worked together to further enhance the technology. Dr. Brekhman's lifetime of research culminated with the development of PrimeQuest Products called:
PRIME 1- Supports Resistance and Immune System while improving recovery time after workouts.
PRIME PLUS - Enhances Athletic Performance, Endurance and Workout productivity.
PRIME PERFECT - Provides the ultimate Weight Loss capabilities while maximizing the body's ability to change fat into muscle.
The following are some of the areas that the adaptogens will benefit:
STRESS PROTECTIVE ACTION
IMMUNE SYSTEM
PHYSICAL WORK CAPACITY
MENTAL WORK CAPACITY
PERFORMANCE, ENDURANCE AND REHABILITATION
NORMALIZING EFFECT
NON-SPECIFIC RESISTANCE
ANTIOXIDANT, ANTI-AGING ACTION
CARDIOVASCULAR SYSTEM
EYESIGHT, COLOR PERCEPTION, HEARING, AND VESTIBULAR FUNCTIONS
The following is a summary of the research performed in each of these specific categories. For each category, we can provide additional documentation with the names of the research scientists and their associated Institution to verify these findings. Each category above had between 8 and 17 researchers perform the studies for that category. The research was quite extensive.......
Stress is a phenomenon that manifests itself in our bodies in many different ways. Some of the more common symptoms of stress include problems with sleep, depression, anxiety, irritability, and lethargy.
Along with the physical symptoms, the body also has more fundamental biological responses to stress. At the cellular level, stress affects our ability to properly transform glucose into energy. Beta-lipa-proteins build up and inhibit the passage of energy through the cell walls. This reduced energy level not only affects our ability to perform physical functions, but inhibits the proper function of all the body's organs - including the brain.
Perhaps the single most important property of adaptogenic plants is their proven ability to combat stress in all forms. Eleutherococcus, the strongest of the adaptogenic plants, increases the body's resistance to a variety of stressors. Experiments have conclusively demonstrated that Eleutherococcus changes the course of the primary physiological indicators of stress by reducing the activation of the adrenal cortex.
Rhodiola rosea leads to an increase in the amount of basic b-endorphin in the blood plasma which inhibits the hormonal changes indicative of stress.
Research by scientists shows that adaptogens, which are an integral part of the PrimeQuest product formulation, allow the body to more ably cope with stress, whether it is daily, extreme, acute or chronic.
Studies show that the adaptogenic extracts included in the unique formula for Prime 1 render vital support to the immune system. For example, in one study of healthy volunteers, a general enhancement of the activation state of T-lymphocytes was observed after administering Eleutherococcus. T-lymphocyte cells are also called "killer cells" because they attack and destroy various viruses. Another study revealed that Eleutherococcus extract augments the phagocytic activity of the peripheral blood leukocytes and favors the reduction of pathological fora on the surface of the skin, indicating an increase in the bodies non specific resistance. The effect of adaptogens, manifested by their ability to induce the formation of endogenic interferon (intracellular development of basic anti- viral proteins), reveals essential aspects of their control over the immune and non-specific mechanisms which protect the body from viruses. Adaptogens exert a strong immunomodulatory influence in healthy test subjects and can be considered non-specific immunostimulants.
Research institutions have discovered that this class of plants is vital for enhancing a person's capacity for physical workloads. Adaptogens have been widely used in studies with workers in professions involving intense physical work strain. They significantly improve bodily functions, by enhancing the body's ability to perform physical tasks and to recover after strenuous physical activity. For example, in tests on six hundred fifty-five healthy men, all of whom were employed as flight personnel (pilots, navigators, radio operators), Eleutherococcus, Aralia and Schizandra accelerated recovery processes following tiresome flight schedules. The subjects' physiological state improved significantly within three hours of a flight to levels even higher than prior to the flight.
In one long range study involving 60 thousand people conducted over a ten year period at the Volzhsky Automobile Factory in Tolyatti, Russia, absence and disability were reduced by 20-30% after taking Eleutherococcus. A 30-50 percent decrease in cases of influenza and a general improvement in health were also noted.
Along with the research which proved adaptogens' value for improving physical work, research studies involving various tests of mental acuity have demonstrated that adaptogens also have the ability to increase a person's metal work capacity. That is, they increase both the amount of mental exercise a person can carry out, as well as the quality of that work. For example, Schizandrachinensis and Rhaponticum carthamoides exerted a strong stimulative influence among test subjects who displayed a great improvement in reading comprehension, aptitude and speed. Rhodiola rosea and Aralia mandshurica enhance a person's ability for memorization and prolonged concentration. In proofreading tests, after taking Rhodiola extract, a decrease in the quantity of mistakes was observed in 88 percent of the experimental group, while an increase in the quantity of mistakes was observed in 54 percent of the control group.
Eleutherococcus senticosus, the 'king' of adaptogens has been shown to increase mental capacity by improving reflex action, attention span, and the precision of performed work. Improvement in hearing, eyesight and motor coordination was also an additional benefit noted in these studies.
Adaptogens provide the basis through which people can build up an energy reserve to be tapped when the body needs it most - under extreme physical condition and during recovery from fatigue. Test subjects administered adaptogenic extracts rapidly displayed improved indicators of energy and endurance, and athletes were able to improve greatly the results of their athletic endeavors.
In one study, under exhausted muscle workloads, it was revealed that Rhodiola extract increased the activity of proteolic enzymes and also significantly increased the level of protein and RNA in the skeletal muscles.
In another study involving a college basketball team, it was revealed that all four parameters of work capacity (including VO2 max, O, pulse max, total work and exhaustion time) showed significantly larger increases when Eleutherococcus was administered than when the subjects were given a placebo. After administering Schizandra in an experiment on 140 athletes, 74 percent of the test subjects attained their best results in a three thousand meter run. Observations were also conducted on weightlifters, wrestlers and gymnasts. Based on the data obtained, it was concluded that eleutherococcus extract increased physical work capacity, decreased fatigue and improved the general mental and physical state of the test subjects.
In an experiment on healthy male athletes, adaptogen administration induced a 64 percent increase in work endurance, while a higher rate of cases with reduced blood lactate and consistently lower blood pressure was also reported.
A study of people performing physical labor revealed that when Eleutherococcus, Rhaponticum carthamoides and Rhodiola were administered, all test subjects showed an improvement in their general, physical and mental states. There was also an improvement in functional indicators (pulse, arterial pressure, vital capacity, back muscle strength, hand endurance under static tension, coordination of movement) and a reduction in the duration of the recovery period in all test subjects.
Through extensive experiments on swimmers, skiers and other athletes, scientists around the world have reliably demonstrated the value of adaptogens for increasing stamina and accelerating the recovery processes after physical exertion.
The adaptogenic ingredients of Prime 1 and Prime Plus have an important normalizing effect on all bodily functions. In studies of an icebreaker's crew on an extended Arctic voyage, after four months of sailing, Rhaponticum extract had a normalizing affect on the central nervous and cardiovascular systems, leading to improved speech, appetite, mood, general mental and physical state and general enhancement of the functional ability of humans under working conditions.
In experiments simulating the affects of extreme changes in altitude on mountain rescue workers, the normalizing action of adaptogens on metabolic disorders occurring under such conditions was revealed. According to the data, adaptogens have a normalizing action on the synthesis of RNA during stress. Adaptogens also contribute to the normalization of protein, vitamin and water salt metabolism. Extremes in bodily functions like high cholesterol, low hemoglobin levels, irregular sugar contents and abnormal blood pressure may be normalized with the support of adaptogens, which activate and regulate normal and efficient blood circulation. At the same time, the use of adaptogens in no way disrupts the function of these bodily systems.
Adaptogens increase the body's non-specific resistance to the harmful influence of various physical factors such as, cooling, overheating, enhanced motor activity, increased or decreased barometric pressure, and ultraviolet or ionizing radiation. Adaptogens have also been shown to increase the body's resistance to the harmful influence of both chemical and biological natures (various toxins, narcotics, hormones, foreign serums, bacteria, etc.. )
Many facts concerning this kind of universal defense action have been obtained for adaptogens. In observations on sailors in the tropics, it was revealed that in 70-75% of the test subjects, Eleutherococcus decreased the manifestation of unfavorable changes in the central nervous system, thermoregulation and hermodynamics (changes associated with the process of adaption to an environment for which the human body is not accustomed.) Eleutherococcus also contributed to an increase in physical and mental work capacity, alleviation of tension in the function of the adrenal glands and improvement in the functional state of the cardiovascular and respiratory systems.
In another study on female vegetable farmers, the body's resistance to harmful environmental factors increased, the general physical and mental state improved, and work productivity increased by 23.5% after taking Eleutherococcus. Eleutherococcus also contributed to better recovery after intense physical work.
Adaptogens also possess an anti-alcohol action decreasing the desire for alcohol. In one observation involving 148 people, the favorable anti-alcohol action of Eleutherococcus was noted in 73% of the test subjects in the experimental group.
As a part of their normal function, body cells make toxic molecules called free radicals - each molecule is missing an electron. Because the free radical molecule "wants" its full electron compliment, it reacts with any module from which it can take an electron. When the free radical takes an electron from certain key components in the cell, such as fat, protein, or DNA molecules, it damages the cell in a process known as oxidation. In addition to free radicals that occur naturally in the body, they also occur as the result of environmental influences. These influences may include ultraviolet radiation or airborne pollutants such as cigarette smoke - both of which contribute to cell oxidation and may accelerate the aging process.
Antioxidants, or oxidation inhibitors, that occur naturally in the human body and in certain foods may block some of this damage by donating electrons to stabilize and neutralize the harmful effects of the free radicals. Adaptogens also possess an antioxidant action. Based on biochemical analysis, adaptogens cause a reliable decrease in total cholesterol and Beta-lipa-proteins, and increase the level of hydrophillic and lipid antioxidants in the blood. In studies by Japanese scientists, it was found that Gomisin N ( a component isolated from Schizandra fruit) is a more active antioxidant than dl-a tocopherol (vitamin E).
Adaptogenic extracts have a favorable influence on the cardiovascular and respiratory systems, providing important support for people carrying out physical work loads. For example, athletes receiving Aralia mandshurica and working out heavily experienced a lower demand on the cardiovascular system. In another observation of shift workers in a Siberian gas industry, the favorable influence of Eleutherococcus on the dynamics of the cardiovascular system and its protective affects during severe climatic and working conditions were also registered.
Adaptogens render a marked cardioprotective effect during painful emotional stress, contributing to a reduction in the adrenoreactivity of the heart and the degree of stress damage to the myocardium.
The adaptogenic plants which comprise the fundamental ingredients of PrimeQuest products have been shown through extensive laboratory study and clinical trials to support and improve the function of the sensory organs. In one study 111,205 physiological tests were conducted to reveal the influence of Eleutherococcus on members of railroad locomotive brigades. The test subjects experienced improved general physical and mental states, increased endurance, improved headache alleviation and prevention, and decreased irritability which is often associated with this high stress occupation. The use of Eleutherococcus also led to improved vision, including increased chromatic stability, improved spectral and contrast sensitivity, improved color differentiation, and increased long distance signal visibility - all of which are crucial to the safety and effectiveness of people in this occupation.
In another study on 156 people exposed to industrial noise, after taking Eleutherococcus, all the participants reported a marked improvement in their general physical and mental condition, an increase in productivity, and alleviation or complete elimination of ringing in the ears, and an improvement in general hearing ability.
In yet another study on 65 healthy individuals, namely air, sea, rail and automobile commuters or employees, using Eleutherococcus extract led to alleviation or elimination of discomfort for those suffering from motion sickness and the general discomforts associated with travel.
Schizandra proves particularly valuable for sharpening the eyesight, while Aralia reliably improves perceptual acuity in skill tests. In wide trials, these natural substances have proven to be extremely valuable for professionals whose occupations bring heavy demands on the eyes, ears, and other senses. In every study, among pilots, machine operators, astronauts, and factory workers, the sensory functions have shown significant improvement under the influence of the various adaptogens.
END OF RESEARCH SUMMARY
Doctor's Medical journal report Adaptogens: Nature's Answer to Stress
Read a few excerpts about adaptogens from Harvey Diamond's Book, "You Can Prevent Breast Cancer"
Scientific Research Summary of Adaptogen Benefits
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